Article
Transspecies dimorphic allelic lineages of the proteasome subunit beta-type 8 gene (PSMB8) in the teleost genus Oryzias.
Proceedings of the National Academy of Sciences of the United States of America - 14 Dec 2010
Miura Fumi, Tsukamoto Kentaro, Mehta Ratnesh Bhai, Naruse Kiyoshi, Magtoon Wichian, Nonaka Masaru
Abstract excerpt
The proteasome subunit β-type 8 (PSMB8) gene in the jawed vertebrate MHC genomic region encodes a catalytic subunit of the immunoproteasome involved in the generation of peptides to be presented by the MHC class I molecules. A teleost, the medaka (Oryzias latipes), has highly diverged dimorphic allelic lineages of the PSMB8 gene with only about 80% amino acid identity, termed "PSMB8d" and "PSMB8N," which have...
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