Article
Genome-wide network analysis of Wnt signaling in three pediatric cancers.
Scientific reports - 17 Oct 2013
Bao Ju, Lee Ho-Jin, Zheng Jie J
Abstract excerpt
Genomic structural alteration is common in pediatric cancers, and analysis of data generated by the Pediatric Cancer Genome Project reveals such tumor-related alterations in many Wnt signaling-associated genes. Most pediatric cancers are thought to arise within developing tissues that undergo substantial expansion during early organ formation, growth and maturation, and Wnt signaling plays an important role in...
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