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Article

Variants of unknown significance in BRCA testing: impact on risk perception, worry, prevention and counseling.

Annals of oncology : official journal of the European Society for Medical Oncology - 1 Nov 2013

Richter S, Haroun I, Graham T C, Eisen A, Kiss A, Warner E

Abstract excerpt

BACKGROUND: Sequence-based BRCA testing can identify variants of unknown significance (VUS). Relatively little is known about how well a test outcome of VUS is understood by patients and referring physicians, and whether genetic counselors have an interest in the development of VUS management guidelines. DESIGN: Self-administered questionnaires were completed by 36 VUS counselees, 75 women with a BRCA mutation...

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Source

Identifiers

PMID: 24131974
DOI: 10.1093/annonc/mdt312

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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