Article
Virus encoded MHC-like decoys diversify the inhibitory KIR repertoire.
PLoS computational biology - 1 Jan 2013
Carrillo-Bustamante Paola, Keşmir Can, de Boer Rob J
Abstract excerpt
Natural killer (NK) cells are circulating lymphocytes that play an important role in the control of viral infections and tumors. Their functions are regulated by several activating and inhibitory receptors. A subset of these receptors in human NK cells are the killer immunoglobulin-like receptors (KIRs), which interact with the highly polymorphic MHC class I molecules. One important function of NK cells is to...
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