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Article

CD81 sequence and susceptibility to hepatitis C infection.

Journal of medical virology - 1 Jan 2014

Houldsworth Annwyne, Metzner Magdalena M, Demaine Andrew, Hodgkinson Andrea, Kaminski Edward, Cramp Matthew

Abstract excerpt

Several cell surface molecules have hepatitis C virus (HCV) binding properties and may serve as receptors facilitating viral entry into cells. The large extracellular loop (LEL) of CD81 has been shown to bind the HCV envelope protein E2 with several critical residues for the CD81-HCV-E2 interaction. It was hypothesised that variation in the CD81 LEL sequence may modify susceptibility to HCV infection. HCV RNA...

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Identifiers

PMID: 24122777
DOI: 10.1002/jmv.23726

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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