Ultrastructure of cisternal synapses on outer hair cells of the mouse cochlea.

doi:10.1002/cne.23478

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Article

Ultrastructure of cisternal synapses on outer hair cells of the mouse cochlea.

The Journal of comparative neurology - 15 Feb 2014

Fuchs Paul Albert, Lehar Mohamed, Hiel Hakim

Abstract excerpt

C (cisternal) synapses with a near membrane postsynaptic cistern are found on motor neurons and other central neurons, where their functional role is unknown. Similarly structured cisternal synapses mediate cholinergic inhibition of cochlear hair cells via α9α10-containing ionotropic receptors and associated calcium-activated (SK2) potassium channels, providing the opportunity to examine the ultrastructure of...

Topics

Animals
Cochlea
Hair Cells, Auditory, Outer
Imaging, Three-Dimensional
Mice
Mice, Inbred C57BL
Mice, Transgenic
Microscopy, Electron, Transmission
Mutation
Receptors, Nicotinic
Small-Conductance Calcium-Activated Potassium Channels
Synapses

Source

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Identifiers

PMID: 24122766
DOI: 10.1002/cne.23478
PMCID: PMC4474150

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