Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Vesicle sub-pool organization at inner hair cell ribbon synapses.

EMBO reports - 1 Nov 2018

Chakrabarti Rituparna, Michanski Susann, Wichmann Carolin

Abstract excerpt

The afferent inner hair cell synapse harbors the synaptic ribbon, which ensures a constant vesicle supply. Synaptic vesicles (SVs) are arranged in morphologically discernable pools, linked via filaments to the ribbon or the presynaptic membrane. We propose that filaments play a major role in SV resupply and exocytosis at the ribbon. Using advanced electron microscopy, we demonstrate that SVs are organized in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Membrane
Share to Deafness
Share to Exocytosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hair Cells, Auditory, Inner

Share to Mice, Mutant Strains

Share to Microscopy, Electron, Transmission

Share to Synapses

Share to Synaptic Vesicles

Source

Open in PubMed Open full text

Identifiers

PMID: 30201800
DOI: 10.15252/embr.201744937
PMCID: PMC6216280

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Vesicle sub-pool organization at inner hair cell ribbon synapses.PMID 30201800Read ↗

Synaptic Ribbons Require Ribeye for Electron Density, Proper Synaptic Localization, and Recruitment of Calcium Channels.Semantic proximity Read ↗

Innervation regulates synaptic ribbons in lateral line mechanosensory hair cells.Semantic proximity Read ↗

Three-dimensional structure of inner ear hair cell mitochondrial networks and ribbon synapses in a zebrafish model of Usher syndrome type 1BSemantic proximity Read ↗

Developmental refinement of hair cell synapses tightens the coupling of Ca2+ influx to exocytosis.Semantic proximity Read ↗

VGLUT3-p.A211V variant fuses stereocilia bundle and elongates synaptic ribbons in the human deafness DFNA25Semantic proximity Read ↗

Structure and function of otoferlin, a synaptic protein of sensory hair cells essential for hearingSemantic proximity Read ↗

Ribbon synapses in zebrafish hair cells.Semantic proximity Read ↗

Functional and developmental changes in the inner hair cell ribbon synapses caused by Myosin VI knockout and deafness-inducing point mutationSemantic proximity Read ↗

Otoferlin: a multi-C2 domain protein essential for hearing.Semantic proximity Read ↗

Disruption of the presynaptic cytomatrix protein bassoon degrades ribbon anchorage, multiquantal release, and sound encoding at the hair cell afferent synapse.Semantic proximity Read ↗

Rabconnectin3α promotes stable activity of the H+ pump on synaptic vesicles in hair cells.Semantic proximity Read ↗

Fife organizes synaptic vesicles and calcium channels for high-probability neurotransmitter release.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.