Article
Vesicle sub-pool organization at inner hair cell ribbon synapses.
EMBO reports - 1 Nov 2018
Chakrabarti Rituparna, Michanski Susann, Wichmann Carolin
Abstract excerpt
The afferent inner hair cell synapse harbors the synaptic ribbon, which ensures a constant vesicle supply. Synaptic vesicles (SVs) are arranged in morphologically discernable pools, linked via filaments to the ribbon or the presynaptic membrane. We propose that filaments play a major role in SV resupply and exocytosis at the ribbon. Using advanced electron microscopy, we demonstrate that SVs are organized in...
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