Article
Identification of a glutamic acid repeat polymorphism of ALMS1 as a novel genetic risk marker for early-onset myocardial infarction by genome-wide linkage analysis.
Circulation. Cardiovascular genetics - 1 Dec 2013
Ichihara Sahoko, Yamamoto Ken, Asano Hiroyuki, Nakatochi Masahiro, Sukegawa Mayo, Ichihara Gaku, Izawa Hideo, Hirashiki Akihiro, Takatsu Fumimaro, Umeda Hisashi, Iwase Mitsunori, Inagaki Haruo, Hirayama Haruo, Sone Takahito, Nishigaki Kazuhiko, Minatoguchi Shinya, Cho Myeong-Chan, Jang Yangsoo, Kim Hyo-Soo, Park Jeong E, Tada-Oikawa Saeko, Kitajima Hidetoshi, Matsubara Tatsuaki, Sunagawa Kenji, Shimokawa Hiroaki, Kimura Akinori, Lee Jong-Young, Murohara Toyoaki, Inoue Ituro, Yokota Mitsuhiro
Abstract excerpt
BACKGROUND: Myocardial infarction (MI) is a leading cause of death worldwide. Given that a family history is an independent risk factor for coronary artery disease, genetic variants are thought to contribute directly to the development of this condition. The identification of susceptibility genes for coronary artery disease or MI may thus help to identify high-risk individuals and offer the opportunity for...
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