Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between tumor necrosis factor-alpha and Fc-gamma receptor polymorphisms with infliximab in Crohn's disease.

Hepato-gastroenterology - 1 Jan 2000

Tomita Kazumitsu, Chiba Toshimi, Sugai Tamotsu, Habano Wataru

Abstract excerpt

BACKGROUND/AIMS: The associations between tumor necrosis factor-alpha (TNF-alpha) and Fcgamma receptor (FcgammaR) polymorphisms with infliximab (IFX) treatment of Crohn's disease (CD) are not well known. The aim of this study was to evaluate the association between these polymorphisms and IFX treatment of CD. METHODOLOGY: DNA was obtained from 41 CD patients (13 females, 28 males). TNF-alpha and FcgammaR...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Antibodies, Monoclonal
Share to Crohn Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GPI-Linked Proteins

Share to Infliximab

Share to Polymorphism, Genetic

Share to Receptors, IgG

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 20698223

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between tumor necrosis factor-alpha and Fc-gamma receptor polymorphisms with infliximab in Crohn's disease.PMID 20698223Read ↗

Role of TNFRSF1B polymorphisms in the response of Crohn's disease patients to infliximab.Semantic proximity Read ↗

Influence of variants of Fc gamma receptors IIA and IIIA on the American College of Rheumatology and European League Against Rheumatism responses to anti-tumour necrosis factor alpha therapy in rheumatoid arthritis.Semantic proximity Read ↗

Evaluation of tumor necrosis factor (TNF)-α mRNA expression level and the rs1799964 polymorphism of the TNF-α gene in peripheral mononuclear cells of patients with inflammatory bowel diseasesSemantic proximity Read ↗

Genetic polymorphisms predict response to anti-tumor necrosis factor treatment in Crohn's disease.Semantic proximity Read ↗

Investigation of the prognostic value of TNF-alpha gene polymorphism among patients treated with infliximab, and the effects of infliximab therapy on TNF-alpha production and apoptosis.Semantic proximity Read ↗

Genetic Polymorphisms on TNFA, TNFRSF1A, and TNFRSF1B Genes Predict the Effectiveness of Anti-TNF-α Treatment in Inflammatory Bowel Disease PatientsSemantic proximity Read ↗

Genetic polymorphisms of tumour necrosis factor receptor superfamily 1b and fas ligand are associated with clinical efficacy and/or acute severe infusion reactions to infliximab in Crohn's disease.Semantic proximity Read ↗

Fc-gamma receptors type3A (rs396991) genotyping for predicting infliximab efficacy and immunogenicity in ulcerative colitis: An observational study of Iraqi cohort.Semantic proximity Read ↗

Genetic polymorphisms of tumour necrosis factor receptor superfamily 1A and 1B affect responses to infliximab in Japanese patients with Crohn's disease.Semantic proximity Read ↗

Polymorphisms in apoptosis genes predict response to infliximab therapy in luminal and fistulizing Crohn's disease.Semantic proximity Read ↗

Disease activity, ANCA, and IL23R genotype status determine early response to infliximab in patients with ulcerative colitis.Semantic proximity Read ↗

Fcgamma receptor type IIIA polymorphisms influence treatment outcomes in patients with inflammatory arthritis treated with tumor necrosis factor alpha-blocking agents.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.