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Article

Alpha-fetoprotein, a fascinating protein and biomarker in neurology.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society - 1 May 2014

Schieving J H, de Vries M, van Vugt J M G, Weemaes C, van Deuren M, Nicolai J, Wevers R A, Willemsen M A

Abstract excerpt

Alpha-fetoprotein (AFP) is present in fetal serum in concentrations up to 5,000,000 μg/l. After birth, AFP gene expression is turned down with a subsequent fall of the serum concentrations of this albumin-like protein to 'adult values' of circa 0.5-15 μg/l from the age of 2 years onwards. Irrespective of its assumed important functions, individuals with AFP deficiency appear fully healthy. The other way around,...

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Source

Identifiers

PMID: 24120489
DOI: 10.1016/j.ejpn.2013.09.003

Genes

AFP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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