Article
Alpha-fetoprotein structure and function: relevance to isoforms, epitopes, and conformational variants.
Experimental biology and medicine (Maywood, N.J.) - 1 May 2001
Mizejewski G J
Abstract excerpt
Mammalian alpha-fetoprotein (AFP) is classified as a member of the albuminoid gene superfamily consisting of albumin, AFP, vitamin D (Gc) protein, and alpha-albumin. Molecular variants of AFP have long been reported in the biomedical literature. Early studies identified isoelectric pH isoforms and lectin-binding variants of AFP, which differed in their physicochemical properties, but not in amino acid...
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