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Biological role of α-fetoprotein in cancer: prospects for anticancer therapy

1 Dec 2002

Abstract excerpt

alpha-fetoprotein has long been considered the 'gold-standard' in the field of tumor markers. During the several decades since the recognition of mammalian alpha-fetoprotein as a tumor-associated fetal protein, it has been purified, characterized, cloned and sequenced for use in the clinical diagnostic laboratory. However, the biological role of alpha-fetoprotein in the regulation of cancer growth has received...

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PMID: 12503217
DOI: 10.1586/14737140.2.6.709

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