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Article

Protein export by the mycobacterial SecA2 system is determined by the preprotein mature domain.

Journal of bacteriology - 1 Feb 2013

Feltcher Meghan E, Gibbons Henry S, Ligon Lauren S, Braunstein Miriam

Abstract excerpt

At the core of the bacterial general secretion (Sec) pathway is the SecA ATPase, which powers translocation of unfolded preproteins containing Sec signal sequences through the SecYEG membrane channel. Mycobacteria have two nonredundant SecA homologs: SecA1 and SecA2. While the essential SecA1 handles "housekeeping" export, the nonessential SecA2 exports a subset of proteins and is required for Mycobacterium...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23204463
DOI: 10.1128/JB.02032-12
PMCID: PMC3562099

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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