Article
Hepatitis C virus 5' untranslated region variability correlates with treatment outcome.
Journal of viral hepatitis - 1 Aug 2014
Bukowska-Ośko I, Radkowski M, Pawełczyk A, Rosinska M, Caraballo Cortés K, Płoski R, Berak H, Horban A, Stanczak J, Fic M, Laskus T
Abstract excerpt
Hepatitis C virus (HCV) variability affects viral-host interactions. We analysed HCV 5'untranslated region (5'UTR) in sera and peripheral blood mononuclear cells (PBMC) from chronic hepatitis C patients undergoing antiviral treatment. We studied 139 patients treated with pegylated interferon and ribavirin. The primary endpoint was a sustained virological response (SVR) defined as negative HCV RNA level 24 weeks...
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