Article
ISDR pattern and evolution in patients with chronic hepatitis C treated with standard or PEG-IFN plus ribavirin.
Antiviral therapy - 1 Apr 2003
Cappiello Giuseppina, Abbate Isabella, Lo Iacono Oreste, Longo Roberta, Solmone Mariacarmela, Ferraro Donatella, Antonucci Giorgio, Di Marco Vito, Di Stefano Rosa, Craxi Antonio, Ippolito Giuseppe, Capobianchi Maria Rosaria
Abstract excerpt
The aim of the study was to characterize the interferon sensitivity determining region (ISDR) mutation pattern and its changes at 4 weeks of treatment in a population of patients infected with hepatitis C virus (HCV) genotype 1b receiving standard or PEG-IFN plus ribavirin (RBV), to find possible early correlates of therapy outcome. Forty-five patients with chronic hepatitis due to HCV 1b were treated by...
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