Article
Small MAF genes variants and chronic myeloid leukemia.
European journal of haematology - 1 Jan 2014
Martínez-Hernández Angelica, Gutierrez-Malacatt Humberto, Carrillo-Sánchez Karol, Saldaña-Alvarez Yolanda, Rojas-Ochoa Alberto, Crespo-Solis Erick, Aguayo-González Alvaro, Rosas-López Adriana, Ayala-Sanchez Jose Manuel, Aquino-Ortega Xochitl, Orozco Lorena, Cordova Emilio J
Abstract excerpt
Chronic myeloid leukemia (CML) is one of the most frequent hematological neoplasia worldwide. The abnormal accumulation of reactive oxygen species may be an important factor in CML development. The transcription factor NRF2 can regulate the transcription of a battery of antioxidant and detoxificant genes after heterodimerizing with small-Maf proteins. Although the participation of NRF2 in the development of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.