Article
Association study of DKK2 polymorphisms with alcohol dependence and alcohol-related harm.
Alcoholism, clinical and experimental research - 1 Feb 2014
Kim Jason Yongha, Bae Joon Seol, Park Byung Lae, Kim Jeong-Hyun, Kim Lyoung Hyo, Kim Jee Wook, Lee Boung Chul, Kang Tae-Cheon, Choi Ihn-Geun, Shin Hyoung Doo
Abstract excerpt
BACKGROUND: Alcohol dependence (AD) is a common disorder with both environmental and genetic factors. Previous studies have shown that the genomic region from chromosome 4q22-q32 is closely associated with AD. Furthermore, a study with Irish subjects revealed that the polymorphisms of Dickkopf WNT signaling pathway inhibitor (DKK2), located at 4q25, showed a significant association with AD. METHODS: We conducted...
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