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Article

Differential expression and activation of epidermal growth factor receptor 1 (EGFR1), ERK, AKT, STAT3, and TWIST1 in nonsmall cell lung cancer (NSCLC).

Experimental lung research - 1 Nov 2013

Gorgisen Gokhan, Ozes Derya, Pehlivanoglu Suray, Erdogan Abdullah, Dertsiz Levent, Ozbilim Gulay, Ozbudak Irem Hicran, Savas Burhan, Ozes Osman Nidai

Abstract excerpt

Lung cancer is the leading cause of death of both men and women across the world. Overexpression and activating mutations of the epidermal growth factor receptor-1 (EGFR1) are frequently observed and associated with poor prognosis. To inhibit the function of EGFR1, multiple antibodies and small-molecule tyrosine kinase inhibitors (TKI) that target EGFR1 have been developed. Even though some patients respond to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24117170
DOI: 10.3109/01902148.2013.831960

Genes

STAT3
TWIST1
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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