Article
UNC5B receptor deletion exacerbates tissue injury in response to AKI.
Journal of the American Society of Nephrology : JASN - 1 Feb 2014
Ranganathan Punithavathi, Jayakumar Calpurnia, Navankasattusas Sutip, Li Dean Y, Kim Il-man, Ramesh Ganesan
Abstract excerpt
Netrin-1 regulates cell survival and apoptosis by activation of its receptors, including UNC5B. However, the in vivo role of UNC5B in cell survival during cellular stress and tissue injury is unknown. We investigated the role of UNC5B in cell survival in response to stress using mice heterozygous...
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