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Review article What causes alzheimer’s disease?

1 Jan 2013

Abstract excerpt

Since the earliest descriptions of Alzheimer's disease (AD), many theories have been advanced as to its cause. These include: (1) exacerbation of aging, (2) degeneration of anatomical pathways, including the cholinergic and cortico-cortical pathways, (3) an environmental factor such as exposure to aluminium, head injury, or malnutrition, (4) genetic factors including mutations of amyloid precursor protein (APP)...

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PMID: 24114635
DOI: 10.5114/fn.2013.37702

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