Article
Epidemiology and etiology of Alzheimer's disease: from genetic to non-genetic factors.
Current Alzheimer research - 1 Oct 2013
Jiang Teng, Yu Jin-Tai, Tian Yan, Tan Lan
Abstract excerpt
At present, the etiology of Alzheimer's disease (AD) is still unclear, but both genetic and non-genetic factors are thought to take part in the etiopathogenesis of AD. Epidemiologic researches revealed that genetic factors played a decisive role in the development of both early-onset AD (EOAD) and late-onset AD (LOAD). The mutations in APP, PSEN1 and PSEN2 are inherited in a Mendelian fashion and directly lead to...
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