Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Familial Alzheimer's disease: genetic influences on the disease process (Review).

International journal of molecular medicine - 1 Nov 1999

Lippa C F

Abstract excerpt

Alzheimer's disease (AD) has both genetic and environmental etiologies. Genetic causes include presenilin (PS) mutations on chromosomes 1 and 14, and amyloid precursor protein (APP) mutations on chromosome 21. At least two susceptibility genes also exist. In this review phenotypic differences in AD groups are described and possible differences in the mechanism(s) by which AD mutations lead to dementia are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Amyloid beta-Protein Precursor
Share to Brain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Family Health

Share to Genetic Predisposition to Disease

Share to Membrane Proteins

Share to Phenotype

Share to Presenilin-1

Source

Identifiers

PMID: 10534576
DOI: 10.3892/ijmm.4.5.529

Genes

APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Familial Alzheimer's disease: genetic influences on the disease process (Review).PMID 10534576Read ↗

[Etiology and genetics of Alzheimer disease].Semantic proximity Read ↗

Molecular genetics of Alzheimer's disease.Semantic proximity Read ↗

Genetic underpinnings in Alzheimer's disease - a review.Semantic proximity Read ↗

Genetic aspects of Alzheimer's diseaseSemantic proximity Read ↗

The genetics and molecular pathology of Alzheimer's disease: roles of amyloid and the presenilins.Semantic proximity Read ↗

Alzheimer's Disease: An Updated Overview of Its Genetics.Semantic proximity Read ↗

Alzheimer’s Disease: Molecular Mechanisms of the Disease and Involved Factors — A Comprehensive Narrative ReviewSemantic proximity Read ↗

Molecular biology and genetics of Alzheimer's diseaseSemantic proximity Read ↗

Molecular genetics of Alzheimer's disease and aging.Semantic proximity Read ↗

Causative and susceptibility genes for Alzheimer's disease: a review.Semantic proximity Read ↗

[Genetic aspects of Alzheimer's disease (Review)].Semantic proximity Read ↗

Genetic basis of neurodegeneration in familial Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.