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Article

Alzheimer's disease: molecular concepts and therapeutic targets.

Die Naturwissenschaften - 1 Jun 2001

Fassbender K, Masters C, Beyreuther K

Abstract excerpt

The beta amyloid peptide is the major component of the neuritic plaques, the characteristic lesions in Alzheimer's disease. Mutations in three genes (APP, PS-1, and PS-2) cause familial Alzheimer's disease by alteration of the rate of generation of amyloid peptide or the length of this peptide. H...

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Identifiers

PMID: 11544953
DOI: 10.1007/s001140100237

Genes

APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11544953-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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