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Article

Identification of single nucleotide polymorphisms in hematopoietic cell transplant patients affecting early recognition of, and response to, endotoxin.

Innate immunity - 1 Oct 2014

Guinan Eva C, Palmer Christine D, Mancuso Christy J, Brennan Lisa, Stoler-Barak Liat, Kalish Leslie A, Suter Eugenie E, Gallington Leighanne C, Huhtelin David P, Mansilla Maria, Schumann Ralf R, Murray Jeffrey C, Weiss Jerrold, Levy Ofer

Abstract excerpt

Hematopoietic cell transplant (HCT) is a life-saving therapy for many malignant and non-malignant bone marrow diseases. Associated morbidities are often due to transplant-related toxicities and infections, exacerbated by regimen-induced immune suppression and systemic incursion of bacterial products. Patients undergoing myeloablative conditioning for HCT become endotoxemic and display blood/plasma changes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24107515
DOI: 10.1177/1753425913505122
PMCID: PMC4128912

Genes

LBP
BPI
TLR4
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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