Article
Host cell-pathogen interface: molecular mechanisms and genetics.
Vaccine - 6 Dec 2004
Schumann Ralf R
Abstract excerpt
Host factors determining the host-pathogen interaction are crucial for the reaction pattern leading to the threat of nosocomial infections. A soluble protein with the ability to recognize a variety of microorganisms is LPS binding protein (LBP). The recently identified family of Toll-like receptors (TLRs) represents the major group of cellular signaling receptors for pathogens. The discovery of genetic variations...
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