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Article

Candidate gene polymorphisms in patients with acetaminophen-induced acute liver failure.

Drug metabolism and disposition: the biological fate of chemicals - 1 Jan 2014

Court Michael H, Peter Inga, Hazarika Suwagmani, Vasiadi Magdalini, Greenblatt David J, Lee William M

Abstract excerpt

Acetaminophen is a leading cause of acute liver failure (ALF). Genetic differences might predispose some individuals to develop ALF. In this exploratory study, we evaluated genotype frequency differences among patients enrolled by the ALF Study Group who had developed ALF either intentionally from a single-time-point overdose of acetaminophen (n = 78), unintentionally after chronic high doses of acetaminophen (n...

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Share to Acetaminophen
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chemical and Drug Induced Liver Injury

Share to Cytochrome P-450 CYP3A

Share to Hyaluronan Receptors

Share to Liver Failure, Acute

Share to Polymorphism, Genetic

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Source

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Identifiers

PMID: 24104197
DOI: 10.1124/dmd.113.053546
PMCID: PMC3876784

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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