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Article

Crystal structure of the human short coiled coil protein and insights into SCOC-FEZ1 complex formation.

PloS one - 1 Jan 2013

Behrens Caroline, Binotti Beyenech, Schmidt Carla, Robinson Carol V, Chua John Jia En, Kühnel Karin

Abstract excerpt

The short coiled coil protein (SCOC) forms a complex with fasciculation and elongation protein zeta 1 (FEZ1). This complex is involved in autophagy regulation. We determined the crystal structure of the coiled coil domain of human SCOC at 2.7 Å resolution. SCOC forms a parallel left handed coiled coil dimer. We observed two distinct dimers in the crystal structure, which shows that SCOC is conformationally...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 24098481
DOI: 10.1371/journal.pone.0076355
PMCID: PMC3788124

Genes

SCOC
FEZ1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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