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Article

Identifying functional single nucleotide polymorphisms in the human CArGome.

Physiological genomics - 22 Sept 2011

Benson Craig C, Zhou Qian, Long Xiaochun, Miano Joseph M

Abstract excerpt

Regulatory SNPs (rSNPs) reside primarily within the nonprotein coding genome and are thought to disturb normal patterns of gene expression by altering DNA binding of transcription factors. Nevertheless, despite the explosive rise in SNP association studies, there is little information as to the function of rSNPs in human disease. Serum response factor (SRF) is a widely expressed DNA-binding transcription factor...

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Identifiers

PMID: 21771879
DOI: 10.1152/physiolgenomics.00098.2011
PMCID: PMC3180741

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SRF

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