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5-HT2Receptors Facilitate JC Polyomavirus Entry

3 Oct 2013

Abstract excerpt

The human JC polyomavirus (JCPyV) causes the rapidly progressing demyelinating disease progressive multifocal leukoencephalopathy (PML). The disease occurs most often in individuals with AIDS but also occurs in individuals receiving immunomodulatory therapies for immune-related diseases such as multiple sclerosis. JCPyV infection of host cells requires the pentasaccharide lactoseries tetrasaccharide c (LSTc) and...

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PMID: 24089568
DOI: 10.1128/jvi.02252-13

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