Article
GRK2 Mediates β-Arrestin Interactions with 5-HT 2 Receptors for JC Polyomavirus Endocytosis
14 Jan 2021
Abstract excerpt
As intracellular parasites, viruses require a host cell to replicate and cause disease. Therefore, virus-host interactions contribute to viral pathogenesis. JC polyomavirus (JCPyV) infects most of the population, establishing a lifelong asymptomatic infection within the kidney. Under conditions of severe immunosuppression JCPyV may spread to the central nervous system, causing the fatal demyelinating disease...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
