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Article

Evasion of superinfection exclusion and elimination of primary viral RNA by an adapted strain of hepatitis C virus.

Journal of virology - 1 Dec 2013

Webster Brian, Ott Melanie, Greene Warner C

Abstract excerpt

Cells that are productively infected by hepatitis C virus (HCV) are refractory to a second infection by HCV via a block in viral replication known as superinfection exclusion. The block occurs at a postentry step and likely involves translation or replication of the secondary viral RNA, but the mechanism is largely unknown. To characterize HCV superinfection exclusion, we selected for an HCV variant that could...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24089557
DOI: 10.1128/JVI.02465-13
PMCID: PMC3838274

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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