Low selection pressure aids the evolution of cooperative ribozyme mutations in cells.

Abstract excerpt

Understanding the evolution of functional RNA molecules is important for our molecular understanding of biology. Here we tested experimentally how two evolutionary parameters, selection pressure and recombination, influenced the evolution of an evolving RNA population. This was done using four parallel evolution experiments that employed low or gradually increasing selection pressure, and recombination events...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Directed Molecular Evolution
• Share to Escherichia coli
• Share to Mutation