Article
The shaping and functional consequences of the dosage effect landscape in multiple myeloma.
BMC genomics - 2 Oct 2013
Samur Mehmet K, Shah Parantu K, Wang Xujun, Minvielle Stéphane, Magrangeas Florence, Avet-Loiseau Hervé, Munshi Nikhil C, Li Cheng
Abstract excerpt
BACKGROUND: Multiple myeloma (MM) is a malignant proliferation of plasma B cells. Based on recurrent aneuploidy such as copy number alterations (CNAs), myeloma is divided into two subtypes with different CNA patterns and patient survival outcomes. How aneuploidy events arise, and whether they con...
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