Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A compendium of myeloma-associated chromosomal copy number abnormalities and their prognostic value.

Blood - 14 Oct 2010

Walker Brian A, Leone Paola E, Chiecchio Laura, Dickens Nicholas J, Jenner Matthew W, Boyd Kevin D, Johnson David C, Gonzalez David, Dagrada Gian Paolo, Protheroe Rebecca K M, Konn Zoe J, Stockley David M, Gregory Walter M, Davies Faith E, Ross Fiona M, Morgan Gareth J

Abstract excerpt

To obtain a comprehensive genomic profile of presenting multiple myeloma cases we performed high-resolution single nucleotide polymorphism mapping array analysis in 114 samples alongside 258 samples analyzed by U133 Plus 2.0 expression array (Affymetrix). We examined DNA copy number alterations and loss of heterozygosity (LOH) to define the spectrum of minimally deleted regions in which relevant genes of interest...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Deletion
Share to Chromosomes, Human

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Rearrangement, B-Lymphocyte, Heavy Chain

Share to Kaplan-Meier Estimate

Share to Loss of Heterozygosity

Share to Multiple Myeloma

Share to Translocation, Genetic

Share to Uniparental Disomy

Source

Identifiers

PMID: 20616218
DOI: 10.1182/blood-2010-04-279596

Genes

FAF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A compendium of myeloma-associated chromosomal copy number abnormalities and their prognostic value.PMID 20616218Read ↗

Prognostic significance of copy-number alterations in multiple myeloma.Semantic proximity Read ↗

Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups.Semantic proximity Read ↗

Comprehensive molecular profiling of multiple myeloma identifies refined copy number and expression subtypesSemantic proximity Read ↗

Integrative multi-omics identifies high risk multiple myeloma subgroup associated with significant DNA loss and dysregulated DNA repair and cell cycle pathwaysSemantic proximity Read ↗

Multiple Myeloma Genomics – A Concise ReviewSemantic proximity Read ↗

A Comprehensive Review of the Genomics of Multiple Myeloma: Evolutionary Trajectories, Gene Expression Profiling, and Emerging Therapeutics.Semantic proximity Read ↗

A DNA target-enrichment approach to detect mutations, copy number changes and immunoglobulin translocations in multiple myeloma.Semantic proximity Read ↗

Genomics in Multiple MyelomaSemantic proximity Read ↗

Functional Impact of Genomic Complexity on the Transcriptome of Multiple MyelomaSemantic proximity Read ↗

Integrative multi-omics identifies high risk Multiple Myeloma subgroup associated with significant DNA loss and dysregulated DNA repair and cell cycle pathwaysSemantic proximity Read ↗

Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma.Semantic proximity Read ↗

Molecular characterization of human multiple myeloma cell lines by integrative genomics: Insights into the biology of the diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.