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Article

Leucine supplementation protects from insulin resistance by regulating adiposity levels.

PloS one - 1 Jan 2013

Binder Elke, Bermúdez-Silva Francisco J, André Caroline, Elie Melissa, Romero-Zerbo Silvana Y, Leste-Lasserre Thierry, Belluomo Ilaria, Duchampt Adeline, Clark Samantha, Aubert Agnes, Mezzullo Marco, Fanelli Flaminia, Pagotto Uberto, Layé Sophie, Mithieux Gilles, Cota Daniela

Abstract excerpt

BACKGROUND: Leucine supplementation might have therapeutic potential in preventing diet-induced obesity and improving insulin sensitivity. However, the underlying mechanisms are at present unclear. Additionally, it is unclear whether leucine supplementation might be equally efficacious once obesity has developed. METHODOLOGY/PRINCIPAL FINDINGS: Male C57BL/6J mice were fed chow or a high-fat diet (HFD),...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24086364
DOI: 10.1371/journal.pone.0074705
PMCID: PMC3783457

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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