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The contradictory role of branched-chain amino acids in lifespan and insulin resistance

20 Jun 2023

Abstract excerpt

Branched-chain amino acids (BCAAs; a mixture of leucine, valine and isoleucine) have important regulatory effects on glucose and lipid metabolism, protein synthesis and longevity. Many studies have reported that circulating BCAA levels or dietary intake of BCAAs is associated with longevity, sarcopenia, obesity, and diabetes. Among them, the influence of BCAAs on aging and insulin resistance often present...

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PMID: 37408986
DOI: 10.3389/fnut.2023.1189982

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