Article
A common biological basis of obesity and nicotine addiction.
Translational psychiatry - 1 Oct 2013
Thorgeirsson T E, Gudbjartsson D F, Sulem P, Besenbacher S, Styrkarsdottir U, Thorleifsson G, Walters G B, Furberg H, Sullivan P F, Marchini J, McCarthy M I, Steinthorsdottir V, Thorsteinsdottir U, Stefansson K
Abstract excerpt
Smoking influences body weight such that smokers weigh less than non-smokers and smoking cessation often leads to weight increase. The relationship between body weight and smoking is partly explained by the effect of nicotine on appetite and metabolism. However, the brain reward system is involved in the control of the intake of both food and tobacco. We evaluated the effect of single-nucleotide polymorphisms...
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