Article
Gene-centric analysis of serum cotinine levels in African and European American populations.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Mar 2012
Hamidovic Ajna, Goodloe Robert J, Bergen Andrew W, Benowitz Neal L, Styn Mindi A, Kasberger Jay L, Choquet Helene, Young Taylor R, Meng Yan, Palmer Cameron, Pletcher Mark, Kertesz Stefan, Hitsman Brian, Spring Bonnie, Jorgenson Eric
Abstract excerpt
To date, most genetic association studies of tobacco use have been conducted in European American subjects using the phenotype of smoking quantity (cigarettes per day). However, smoking quantity is a very imprecise measure of exposure to tobacco smoke constituents. Analyses of alternate phenotypes and populations may improve our understanding of tobacco addiction genetics. Cotinine is the major metabolite of...
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