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Article

Novel Phenotype-Genotype Correlations of Restrictive Cardiomyopathy With Myosin-Binding Protein C (MYBPC3) Gene Mutations Tested by Next-Generation Sequencing.

Journal of the American Heart Association - 10 Jul 2015

Wu Wei, Lu Chao-Xia, Wang Yi-Ning, Liu Fang, Chen Wei, Liu Yong-Tai, Han Ye-Chen, Cao Jian, Zhang Shu-Yang, Zhang Xue

Abstract excerpt

BACKGROUND: MYBPC3 dysfunctions have been proven to induce dilated cardiomyopathy, hypertrophic cardiomyopathy, and/or left ventricular noncompaction; however, the genotype-phenotype correlation between MYBPC3 and restrictive cardiomyopathy (RCM) has not been established. The newly developed next-generation sequencing method is capable of broad genomic DNA sequencing with high throughput and can help explore...

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Source

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Identifiers

PMID: 26163040
DOI: 10.1161/JAHA.115.001879
PMCID: PMC4608072

Genes

MYBPC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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