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Article

Effect of soluble inducible costimulator level and its polymorphisms on age-related macular degeneration.

DNA and cell biology - 1 Dec 2013

Yu Honghua, Zou Xiulan, Peng Lianghong, Wang Yong, Zhang Chu, Chen Bin, Zou Yuping

Abstract excerpt

Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly population. Evidence has shown that the human immune system may play critical roles in this disease. Inducible costimulator (ICOS) promotes T-cell activation, differentiation, and T:B-cell interactions. The aim of the study was to understand the effect of ICOS on the development of AMD from genetic polymorphism perspective and...

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Source

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Identifiers

PMID: 24083358
DOI: 10.1089/dna.2013.2127
PMCID: PMC3864366

Genes

ICOS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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