Article
Characterization and mutational analysis of yeast Dbp8p, a putative RNA helicase involved in ribosome biogenesis.
Nucleic acids research - 1 Mar 2001
Daugeron M C, Linder P
Abstract excerpt
RNA helicases of the DEAD box family are involved in almost all cellular processes involving RNA molecules. Here we describe functional characterization of the yeast RNA helicase Dbp8p (YHR169w). Our results show that Dbp8p is an essential nucleolar protein required for biogenesis of the small ribosomal subunit. In vivo depletion of Dbp8p resulted in a ribosomal subunit imbalance due to a deficit in 40S ribosomal...
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