Article
DNA-replication recovery inhibition and subsequent reinitiation in UV-radiation-damaged E. coli: a strategy for survival.
Mutation research - 1 Mar 1990
Doudney C O
Abstract excerpt
Using the incorporation of [14C]thymine to measure DNA accumulation, it was shown that exposure of the B/r strain of Escherichia coli to 10 J/m2 of ultraviolet radiation (UV) inhibits replication for about 20 min, but then resumption of replication occurs. Pulse-labelling with [3H]thymidine after exposure of the WT strain to this fluence confirmed the transient inhibition and recovery of DNA replication. After...
Topics
- DNA Replication
- DNA, Bacterial
- Dose-Response Relationship, Radiation
- Escherichia coli
- Genes, Bacterial
- Mutation
- Rec A Recombinases
- Species Specificity
- Thymidine
- Ultraviolet Rays
