Article
DNA damage-processing in E. coli: on-going protein synthesis is required for fixation of UV-induced lethality and mutation.
DNA repair - 1 Oct 2002
Burger Amanda, Raymer Jenny, Bockrath R
Abstract excerpt
UV irradiation of E. coli produces photoproducts in the DNA genome. In consequence, some bacteria lose viability (colony-forming ability) or remain viable as mutant cells. However, the end-points of viability inactivation (lethality) or mutation are determined by cellular processes that act on the UV-damaged DNA. We have investigated the in vivo time course for processes that deal with cyclobutane pyrimidine...
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