Synapsis-mediated fusion of free DNA ends forms inverted dimer plasmids in yeast.

doi:10.1093/genetics/124.1.67

Back to search

Article

Synapsis-mediated fusion of free DNA ends forms inverted dimer plasmids in yeast.

Genetics - 1 Jan 1990

Kunes S, Botstein D, Fox M S

Abstract excerpt

When yeast (Saccharomyces cerevisiae) is transformed with linearized plasmid DNA and the ends of the plasmid do not share homology with the yeast genome, circular inverted (head-to-head) dimer plasmids are the principal product of repair. By measurements of the DNA concentration dependence of tra...

Topics

Blotting, Southern
DNA, Fungal
Phenotype
Plasmids
Pyrimidine Dimers
Recombination, Genetic
Restriction Mapping
Saccharomyces cerevisiae
Transformation, Genetic

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.