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Article

Synapsis-mediated fusion of free DNA ends forms inverted dimer plasmids in yeast.

Genetics - 1 Jan 1990

Kunes S, Botstein D, Fox M S

Abstract excerpt

When yeast (Saccharomyces cerevisiae) is transformed with linearized plasmid DNA and the ends of the plasmid do not share homology with the yeast genome, circular inverted (head-to-head) dimer plasmids are the principal product of repair. By measurements of the DNA concentration dependence of transformation with a linearized plasmid, and by transformation with mixtures of genetically marked plasmids, we show that...

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Identifiers

PMID: 2407606
DOI: 10.1093/genetics/124.1.67
PMCID: PMC1203910

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Source receipt: pubmed, retrieved 7 Sept 2026.

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