Article
Ends-in vs. ends-out recombination in yeast.
Genetics - 1 Dec 1993
Hastings P J, McGill C, Shafer B, Strathern J N
Abstract excerpt
Integration of linearized plasmids into yeast chromosomes has been used as a model system for the study of recombination initiated by double-strand breaks. The linearized plasmid DNA recombines efficiently into sequences homologous to the ends of the DNA. This efficient recombination occurs both for the configuration in which the break is in a contiguous region of homology (herein called the ends-in...
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