Genetic instability of clathrin-deficient strains of Saccharomyces cerevisiae.

doi:10.1093/genetics/124.1.27

Back to search

Article

Genetic instability of clathrin-deficient strains of Saccharomyces cerevisiae.

Genetics - 1 Jan 1990

Lemmon S K, Freund C, Conley K, Jones E W

Abstract excerpt

Saccharomyces cerevisiae strains carrying a mutation in the clathrin heavy chain gene (CHC1) are genetically unstable and give rise to heterogeneous populations of cells. Manifestations of the instability include increases in genome copy number as well as compensatory genetic changes that allow b...

Topics

Canavanine
Chromosome Mapping
Chromosomes, Fungal
Clathrin
Crosses, Genetic
Drug Resistance, Microbial
Genes, Fungal
Genetic Linkage
Mutation
Polyploidy
Restriction Mapping
Saccharomyces cerevisiae
Suppression, Genetic
Transformation, Genetic

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.