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Article

Suppressors of clathrin deficiency: overexpression of ubiquitin rescues lethal strains of clathrin-deficient Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Jan 1993

Nelson K K, Lemmon S K

Abstract excerpt

Clathrin-mediated vesicular transport is important for normal growth of the yeast Saccharomyces cerevisiae. Previously, we identified a genetic locus (SCD1) that influences the ability of clathrin heavy-chain-deficient (Chc-) yeast cells to survive. With the scd1-v allele, Chc- yeast cells are viable but grow poorly; with the scd1-i allele, Chc- cells are inviable. To identify the SCD1 locus and other genes that...

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Identifiers

PMID: 8380227
DOI: 10.1128/mcb.13.1.521-532.1993
PMCID: PMC358931

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