Article
Doubling Ty1 element copy number in Saccharomyces cerevisiae: host genome stability and phenotypic effects.
Genetics - 1 Dec 1991
Boeke J D, Eichinger D J, Natsoulis G
Abstract excerpt
Haploid yeast strains bearing approximately double the normal number of Ty1 elements have been constructed using marked GAL/Ty1 fusion plasmids. The strains maintain their high transposon copy number and overall genome structure in the absence of selection. The strains bearing extra Ty1 copies ar...
Topics
- Blotting, Southern
- DNA Transposable Elements
- Electrophoresis, Gel, Two-Dimensional
- Gene Amplification
- Genome, Fungal
- Meiosis
- Mitosis
- Phenotype
- Restriction Mapping
- Saccharomyces cerevisiae
