Article
The proline-rich motif of the proDer p 3 allergen propeptide is crucial for protease-protease interaction.
PloS one - 1 Jan 2013
Dumez Marie-Eve, Herman Julie, Campisi Vincenzo, Bouaziz Ahlem, Rosu Frédéric, Luxen André, Vandenberghe Isabel, de Pauw Edwin, Frère Jean-Marie, Matagne André, Chevigné Andy, Galleni Moreno
Abstract excerpt
The majority of proteases are synthesized in an inactive form, termed zymogen, which consists of a propeptide and a protease domain. The propeptide is commonly involved in the correct folding and specific inhibition of the enzyme. The propeptide of the house dust mite allergen Der p 3, NPILPASPNA...
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