MYD88 (L265P) mutation is an independent risk factor for progression in patients with IgM monoclonal gammopathy of undetermined significance

Abstract excerpt

To the editor: MYD88 (L265P) is a recurrent somatic mutation in Waldenstrom macroglobulinemia (WM).[1][1][⇓][2][⇓][3]-[4][4] By means of allele-specific polymerase chain reaction (AS-PCR), the MYD88 mutation is detectable in almost all patients with WM and in roughly half the patients with IgM

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